Spinal Tumors: Diagnosis and Treatment.
Matthew L GoodwinJacob M BuchowskiJoseph H SchwabDaniel M SciubbaPublished in: The Journal of the American Academy of Orthopaedic Surgeons (2022)
Tumors that present in or around the spine can be challenging to diagnose and treat. A proper workup involves a complete history and physical examination, appropriate staging studies, appropriate imaging of the entire spine, and a tissue biopsy. The biopsy defines the lesion and guides treatment, but in some rare instances, rapid neurological decline may lead to urgent or emergent surgery before it can be analyzed. "Enneking-appropriate" margins should remain the goal for primary tumors while adequate debulking/separation/stabilization are often the goals in metastatic disease. Primary tumors of the spine are rare and often complex tumors to operate on-achieving Enneking-appropriate margins provides the greatest chance of survival while decreasing the chance of local recurrence. Metastatic tumors of the spine are increasingly more common, and timing of surgery must be considered within the greater framework of the patient and the patient's disease, deficits, stability, and other treatments available. The specific tumor type will dictate what other multidisciplinary approaches are available, allowing for chemotherapy and radiation as needed.
Keyphrases
- minimally invasive
- squamous cell carcinoma
- small cell lung cancer
- coronary artery bypass
- high resolution
- physical activity
- traumatic brain injury
- neoadjuvant chemotherapy
- lymph node
- ultrasound guided
- mass spectrometry
- coronary artery disease
- acute coronary syndrome
- spinal cord injury
- quantum dots
- fine needle aspiration
- global health
- cerebral ischemia