Effectiveness of the adipose stem cells in burn wound healing: literature review.
Ahmad OryanEffat AlemzadehEsmat AlemzadehMaryam BarghiMohammad ZareiHamid SalehiniyaPublished in: Cell and tissue banking (2021)
Adipose- stem cells (ASCs) have received much attention in the recent years and several articles have investigated the role of these cells on burn wound healing. To understand the outcomes of the ASCs therapy on burn wound healing, a systematic review was performed. This study was conducted by searching in Pubmed, ISI, and Scopus until May 2021. Thirty-six animal studies were included in this study. The findings revealed that although treatment with ASCs somewhat enhanced the healing rate, cultured ASCs on scaffolds or its combination with hydrogels could significantly increase the viability of ASCs and promote rate of healing. However, clinical studies are necessary to gain a better understanding of the role of ASCs in burn wound healing.
Keyphrases
- wound healing
- stem cells
- randomized controlled trial
- adipose tissue
- systematic review
- insulin resistance
- induced apoptosis
- cell therapy
- type diabetes
- endothelial cells
- cell death
- skeletal muscle
- case report
- atomic force microscopy
- oxidative stress
- drug delivery
- mesenchymal stem cells
- glycemic control
- hyaluronic acid
- high speed