Profibrotic VEGFR3-Dependent Lymphatic Vessel Growth in Autoimmune Valvular Carditis.
Victoria OsinskiAmritha YellamilliMaria M FirulyovaMichael J ZhangAlyssa L PeckJennifer L AugerJessica L FaragherAubyn MarathRochus K VoellerTimothy D O'ConnellKonstantin ZaitsevBryce A BinstadtPublished in: Arteriosclerosis, thrombosis, and vascular biology (2024)
These studies reveal a novel mode of inflammation-associated, VEGFR3-dependent postnatal lymphangiogenesis in murine autoimmune valvular carditis, with similarities to human rheumatic heart disease.
Keyphrases
- atrial fibrillation
- multiple sclerosis
- endothelial cells
- vascular endothelial growth factor
- oxidative stress
- rheumatoid arthritis
- aortic valve
- preterm infants
- lymph node
- drug induced
- pulmonary hypertension
- oral anticoagulants
- genome wide
- induced pluripotent stem cells
- single cell
- pluripotent stem cells
- gene expression
- case control