African vs. Caucasian and Asian difference for the association of interleukin-10 promotor polymorphisms with type 2 diabetes mellitus (a meta-analysis study).

This meta-analysis demonstrated that IL-10 - 1082 A > G polymorphism was associated with increased risk of development of T2DM in total subjects no matter was their ethnic background, while both IL-10 - 592 C > A and - 819 C > T polymorphisms were associated with that risk only among African subjects.