TP53 gain-of-function mutation modulates the immunosuppressive microenvironment in non-HPV-associated oral squamous cell carcinoma.
Yewen ShiXiaoyong RenShaolong CaoXi ChenBo YuanFabio Henrique Brasil da CostaAlanis E Rodriguez RosarioArnoldo CoronaChieko MichikawaRatna VeeramachaneniAbdullah A OsmanTongxin XieWenyi WangAndrew G SikoraJeffrey N MyersRoberto RangelPublished in: Journal for immunotherapy of cancer (2023)
gain-of-function mutation modulate the TIME to evade tumor immunity, leading to tumor progression and decreased survival.