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Deuterium MRSI of tumor cell death in vivo following oral delivery of 2 H-labeled fumarate.

Friederike HesseAlan J WrightFlaviu BulatVencel SomaiFelix KreisKevin M Brindle
Published in: Magnetic resonance in medicine (2022)
]fumarate can be used to detect tumor cell death noninvasively following treatment with a sensitivity that is similar to that obtained with intravenous administration.
Keyphrases
  • cell death
  • cell cycle arrest
  • high dose
  • computed tomography
  • combination therapy
  • replacement therapy