Efficacy and Safety of Masitinib in Progressive Forms of Multiple Sclerosis: A Randomized, Phase 3, Clinical Trial.
Patrick VermerschLuis Brieva-RuizRobert J FoxFriedemann PaulLluis Ramio-TorrentaMatthias SchwabAlain MoussyColin MansfieldOlivier HermineMaciej Maciejowskinull nullPublished in: Neurology(R) neuroimmunology & neuroinflammation (2022)
This study provides Class II evidence that masitinib 4.5 mg/kg/d decreased progression of disability, measured by the EDSS, in adults with PPMS or patients with nSPMS (with no exacerbations in the last 2 years).