Treatment with quercetin increases Nrf2 expression and neuronal differentiation of sub ventricular zone derived neural progenitor stem cells in adult rats.

Ali Ebrahimi Kazem Parivar Nasim Hayati-E Roodbari Akram Eidi

Published in: Molecular biology reports (2023)

These findings confirmed the dose-dependent effect of quercetin on proliferation and differentiation of cell. In addition, quercetin increased the expression of Nrf2 gene. By combining these two effects of quercetin, this substance can be considered an effective compound in the treatment of degenerative defects in CNS.

Keyphrases

stem cells
poor prognosis
oxidative stress
gene expression
signaling pathway
genome wide
left ventricular
mesenchymal stem cells
binding protein
copy number
long non coding rna
brain injury
bone marrow
young adults
subarachnoid hemorrhage
atrial fibrillation