The NUTRIENT Trial (NUTRitional Intervention among myEloproliferative Neoplasms): Results from a Randomized Phase I Pilot Study for Feasibility and Adherence.

Laura F Mendez Luque Julio Avelar-Barragan Hellen Nguyen Jenny Nguyen Eli M Soyfer Jiarui Liu Jane H Chen Nitya Mehrotra Xin Helen Huang Heidi E Kosiorek Amylou C Dueck Alexander S Himstead Elena S Heide Melinda Lem Kenza El Alaoui Eduard Mas Robyn M Scherber Ruben A Mesa Katrine L Whiteson Andrew O Odegaard Angela G Fleischman

Published in: Cancer research communications (2024)

Diet is a central tenant of management of chronic conditions characterized by subclinical inflammation, such as cardiovascular disease, but has not entered the treatment algorithm for clonal hematologic disorders. Here, we establish that a Mediterranean diet intervention is feasible in the MPN patient population and can improve symptom burden. These findings warrant large dietary interventions in patients with hematologic disorders to test the impact of diet on clinical outcomes.

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