Low-dose lipopolysaccharide exposure can increase in vivo bilirubin production rates in newborn mice.

Sota IwataniDanielle R JacobsenRonald J WongDavid K Stevenson

Published in: Acta paediatrica (Oslo, Norway : 1992) (2020)

Low-dose LPS treatment can upregulate liver HO-1 expression and may underlie the severe hyperbilirubinaemia seen in septic infants, particularly when undergoing haemolysis.

Keyphrases

low dose
inflammatory response
high dose
poor prognosis
toll like receptor
early onset
lps induced
high fat diet induced
binding protein
adipose tissue
immune response
cell proliferation