False gene and chromosome losses in genome assemblies caused by GC content variation and repeats.

Juwan KimChul LeeByung June KoDong Ahn YooSohyoung WonAdam M PhillippyOlivier FedrigoGuojie ZhangKerstin HoweJonathan WoodRichard DurbinGiulio FormentiSamara BrownLindsey CantinClaudio V MelloSeoae ChoArang RhieHeebal KimErich D Jarvis

Published in: Genome biology (2022)

Our findings reveal novel regulatory landscapes and protein coding sequences that have been greatly underestimated in previous assemblies and are now present in the Vertebrate Genomes Project reference genomes.

Keyphrases

genome wide
copy number
dna methylation
quality improvement
transcription factor
protein protein
amino acid
genome wide identification
gas chromatography
gene expression
high resolution