Effect of Food on the Pharmacokinetics of Tenofovir Amibufenamide: A Phase I, Randomized, Open-Label, Two-Period Crossover Trial in Healthy Adult Subjects.
Jian LiuMinglan WuJiejing KaiMeihua LinYunliang ZhengYiya JiangQian HuangYou ZhaiYunqing QiuPublished in: Drug design, development and therapy (2023)
was delayed and exposures of TMF and TFV were higher than under fasted conditions. The modest changes observed are not considered clinically relevant, so TMF can be taken with or without food.