Mucin Expression and Splicing Determine Novel Subtypes and Patient Mortality in Pancreatic Ductal Adenocarcinoma.

Christopher M ThompsonAndrew Cannon Sean WestDario GhersiPranita AtriRakesh BhatiaLynette M SmithSatyayanarayana RachaganiChristopher WichmanSushil KumarSurinder K Batra

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

Altogether, we demonstrate the unique expression pattern of mucins, four mucin-based PDAC subtypes, and the contribution of MUC1, MUC4, and MUC16 SVs in PDAC patient survival.

Keyphrases

poor prognosis
case report
binding protein
cardiovascular events
long non coding rna
risk factors