The upregulation of these distinctive genes in hypertensive groups compared to normotensives confirmed their diagnostic potential. Therefore, HLA-DRA, MAFF and MEF2A could be candidate markers of HDP, while the MAPK1 gene could be a differentiating marker between early-onset pre-eclampsia and gestational hypertension.
Keyphrases
- early onset
- blood pressure
- weight gain
- late onset
- genome wide
- genome wide identification
- pregnant women
- copy number
- signaling pathway
- bioinformatics analysis
- birth weight
- genome wide analysis
- pregnancy outcomes
- oxidative stress
- body mass index
- dna methylation
- cell proliferation
- poor prognosis
- gene expression
- magnetic resonance imaging
- physical activity
- magnetic resonance
- climate change
- arterial hypertension