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Microbiologic diagnostics and pathogen spectrum in infective endocarditis of surgically treated patients: a five-year, retrospective, monocentric study.

Renate ZieglerHendrik ArnoldRalph BertramWalter GeißdörferMatthias PauschingerTheodor FischleinFrancesco PollariJoerg Steinmann
Published in: Infection (2023)
Blood culture as a comparatively non-invasive and straightforward technique remains an important and reliable method for initial detection of the causative organism in IE. Diagnostic stewardship programs should broadly emphasize proper collection of blood cultures, particularly sampling prior to any antibiotic treatment. Additionally, molecular testing using 16S rDNA tissue PCR can be used with culture techniques to increase the diagnostic yield, especially in the case of a negative blood culture.
Keyphrases
  • end stage renal disease
  • newly diagnosed
  • chronic kidney disease
  • ejection fraction
  • public health
  • prognostic factors
  • real time pcr
  • cross sectional
  • single molecule
  • candida albicans
  • combination therapy
  • acute care