Upregulation of the NKG2D ligand ULBP2 by JC polyomavirus infection promotes immune recognition by natural killer cells.

Stephanie JostJenny AhnSarah ChenTaylor YoderKayitare Eunice GikundiroEsther LeeSimon B GressensKyle KrollMelissa CraemerG Campbell KaynorMichelle LiftonC Sabrina Tan

Published in: The Journal of infectious diseases (2023)

NKG2D-mediated activation of NK cells plays a key role in controlling JCPyV replication and may be a promising immunotherapeutic target to boost NK cell anti-JCPyV activity.

Keyphrases

long non coding rna
nk cells
natural killer cells
poor prognosis
cell proliferation
signaling pathway