Stress ulcer prophylaxis in the intensive care unit trial: detailed statistical analysis plan.
Mette KragA PernerJ WetterslevT LangeM P WiseM BorthwickS BendelP PelosiF KeusA B GuttormsenJ C SchefoldTine Sylvest MeyhoffS MarkerMorten Hylander MöllerPublished in: Acta anaesthesiologica Scandinavica (2017)
Stress ulcer prophylaxis is standard of care in ICUs worldwide, but has never been tested in large high-quality randomised placebo-controlled trials. The SUP-ICU trial will provide important high-quality data on the balance between the benefits and harms of stress ulcer prophylaxis in adult critically ill patients.
Keyphrases
- study protocol
- phase iii
- clinical trial
- placebo controlled
- phase ii
- double blind
- open label
- healthcare
- stress induced
- randomized controlled trial
- palliative care
- intensive care unit
- squamous cell carcinoma
- quality improvement
- machine learning
- electronic health record
- young adults
- pain management
- heat stress
- chronic pain
- acute respiratory distress syndrome
- deep learning
- rectal cancer
- locally advanced