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Fatty acid oxidation is critical for the tumorigenic potential and chemoresistance of pancreatic cancer stem cells.

Marta MascaraqueSarah CourtoisAlba Royo-GarcíaDavid BarnedaAndrei M StoianIsabel VillaosladaPilar Espiau-RomeraAnsooya BokilAndrés Cano-GalianoPetra JagustChristopher HeeschenPatricia Sancho
Published in: Journal of translational medicine (2024)
Targeting FAO inhibition represents a promising therapeutic strategy against this highly tumorigenic population.
Keyphrases
  • cancer stem cells
  • fatty acid
  • cancer therapy
  • hydrogen peroxide
  • drug delivery
  • nitric oxide
  • electron transfer