Analgesic efficacy and safety of ketamine after total knee or hip arthroplasty: a meta-analysis of randomised placebo-controlled studies.
Bei XuYilun WangChao ZengJie WeiJiatian LiZiying WuHongyi HeGuanghua LeiDongxing XieXiang DingPublished in: BMJ open (2019)
Intravenous administration of ketamine is effective and safe for postoperative pain relief in patients undergoing total knee or hip arthroplasty. Nevertheless, the analgesic efficacy and safety of ketamine in such patients seem to vary by different administration routes and still warrant further studies to explore.
Keyphrases
- postoperative pain
- placebo controlled
- patients undergoing
- total knee arthroplasty
- end stage renal disease
- pain management
- double blind
- clinical trial
- ejection fraction
- knee osteoarthritis
- newly diagnosed
- chronic kidney disease
- neuropathic pain
- study protocol
- total hip arthroplasty
- case control
- anterior cruciate ligament
- randomized controlled trial
- squamous cell carcinoma
- high dose
- spinal cord injury
- spinal cord