High levels of pretreatment and acquired HIV drug resistance in Nicaragua: results from the first nationally representative survey, 2016.
Amalia Girón-CallejasClaudia García-MoralesRicardo Mendizabal-BurasteroMatilde RománDaniela Tapia-TrejoMarissa Pérez-GarcíaVerónica S Quiroz-MoralesSandra I JuárezGiovanni RavasiCarlos VargasRené GutiérrezLuz RomeroAleyda SolórzanoEdgar SajquimSanny NorthbrookSantiago Avila-RíosGustavo Reyes-TeránPublished in: Journal of the International AIDS Society (2020)
Despite implementation challenges yielding low-precision HIVDR estimates, high rates of NNRTI PDR were observed in Nicaragua, suggesting consideration of non-NNRTI-based first-line regimens for ART initiators. Strengthened HIVDR monitoring, systematic VL testing, and improved ART adherence support are also warranted.