Synergistic and Additive Effects of Herbal Medicines in Combination with Chemotherapeutics: A Scoping Review.
Taehun JungChunhoo CheonPublished in: Integrative cancer therapies (2024)
Most studies reported synergistic effects on cytotoxicity, apoptosis, and tumor growth inhibition. These effects were found to be associated with cell cycle arrest, anti-angiogenesis, and gene expression regulation. Further studies leading to clinical trials are required. Clinical experiences in East Asian countries could provide insights for future research.
Keyphrases
- cell cycle arrest
- cell death
- gene expression
- pi k akt
- clinical trial
- case control
- cancer therapy
- dna methylation
- mental health
- oxidative stress
- endothelial cells
- signaling pathway
- endoplasmic reticulum stress
- vascular endothelial growth factor
- drug delivery
- randomized controlled trial
- wound healing
- phase ii
- double blind