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Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial.

John A ToddMarina EvangelouAntony J CutlerMarcin L PekalskiNeil M WalkerHelen E StevensLinsey PorterDeborah J SmythDaniel B RainbowRicardo C FerreiraLaura EspositoKara M D HunterKevin W LoudonKathryn IronsJennie H YangCharles J M BellHelen SchuilenburgJames HeywoodBen ChallisSankalpa NeupanePamela ClarkeGillian ColemanSarah DawsonDonna GoymerKaterina AnselmiovaJane KennetJudy BrownSarah L CaddyJia LuJane GreatorexIan GoodfellowChris WallaceTimothy I M TreeMark EvansAdrian P ManderSimon BondLinda S WickerFrank Waldron-Lynch
Published in: PLoS medicine (2016)
ISRCTN Registry ISRCTN27852285; ClinicalTrials.gov NCT01827735.
Keyphrases
  • open label
  • phase iii
  • phase ii
  • study protocol
  • clinical trial
  • phase ii study
  • transcription factor
  • randomized controlled trial
  • double blind
  • placebo controlled
  • squamous cell carcinoma