Pushing the agenda for intravenous push administration in outpatient parenteral antimicrobial therapy.
Tanner M JohnsonLeah C Whitman WebsterMeera MehtaJessica E JohnsonNicolás Cortés-PenfieldChristina G RiveraPublished in: Therapeutic advances in infectious disease (2023)
Intravenous push (IVP) antimicrobial administration refers to rapid bolus infusion of medication. This drug delivery method offers improved patient convenience, superior patient and nursing satisfaction, and cost savings when used in outpatient parenteral antimicrobial therapy (OPAT). Antimicrobial agents must demonstrate optimal physiochemical and pharmacologic characteristics, as well as sufficient syringe stability, to be administered in this manner. Additionally, impacts on medication tolerability, patient safety, and effectiveness must be considered. This narrative review summarizes the available data and practical implications of IVP administration of antimicrobials in the OPAT setting.
Keyphrases
- patient safety
- staphylococcus aureus
- drug delivery
- quality improvement
- healthcare
- case report
- randomized controlled trial
- high dose
- systematic review
- low dose
- mental health
- stem cells
- adverse drug
- electronic health record
- machine learning
- emergency department
- clinical trial
- open label
- bone marrow
- cell therapy
- cancer therapy
- mesenchymal stem cells
- double blind
- study protocol
- patient satisfaction