Treating rheumatoid arthritis with leflunomide monotherapy versus combination therapy with methotrexate.

Daniel Ampessan Guadagnin Leonardo Vinicius Mazzali Thelma Larocca Skare Bárbara Stadler Kahlow

Published in: European journal of rheumatology (2020)

Our results suggest that the efficacy of the combined treatment with MTX and LFN is similar to that of LFN alone. No increase in toxicity was observed with the combination therapy.

Keyphrases

combination therapy
rheumatoid arthritis
high dose
disease activity
randomized controlled trial
clinical trial
systemic sclerosis