Accuracy of single molecular biomarkers in saliva for the diagnosis of periodontitis: A systematic review and meta-analysis.
Nora Arias-BujandaAlba Regueira-IglesiasCarlos Balsa-CastroLuigi NibaliNikos DonosInmaculada Tomás-CarmonaPublished in: Journal of clinical periodontology (2019)
MMP8, MMP9, IL1beta, IL6 and Hb were salivary biomarkers with good capability to detect periodontitis in systemically healthy subjects. MMP8 and IL1beta are the most researched biomarkers in the field, both showing clinically fair effectiveness for the diagnosis of periodontitis.