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Small cell lung cancer responds to immunogenic chemotherapy followed by PD-1 blockade.

Guido KroemerOliver Kepp
Published in: Oncoimmunology (2021)
Sequential combination of immunogenic cell death (ICD)-induced interventions with subsequent immunotherapy has shown efficacy in preclinical models and clinical evaluation. Recently, a clinical trial enrolling small cell lung cancer patients treated with amrubicin together with PD-1 blockade confirmed the notion that ICD sensitizes tumors to immune checkpoint inhibitors.
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