Spatially Resolved Microglia/Macrophages in Recurrent Glioblastomas Overexpress Fatty Acid Metabolism and Phagocytic Genes.

Akshitkumar M Mistry Jonah DaneshmandSeonYeong Jamie SeoNorman L LehmanDonald M MillerDylan A GoodinHermann B FrieboesJoseph ChenAdrianna MastersBrian J WilliamsKavitha Yaddanapudi

Published in: Current oncology (Toronto, Ont.) (2024)

Tumor-associated microglia/macrophages in recurrent GBM overexpress genes involved in fatty acid/lipid metabolism. Further investigation is needed to fully delineate the role of PLD phospholipases in GBM progression.

Keyphrases

fatty acid
inflammatory response
neuropathic pain
genome wide
gene expression
dna methylation
spinal cord