A cookbook for DNase Hi-C.

Maria GridinaEvgeniy MozheikoEmil ValeevLudmila P NazarenkoMaria E LopatkinaZhanna G MarkovaMaria I YablonskayaViktoria Yu VoinovaNadezhda V ShilovaIgor N LebedevVeniamin S Fishman

Published in: Epigenetics & chromatin (2021)

We propose a new robust protocol for the preparation of DNAse Hi-C libraries from cultured human cells and blood samples supplemented with experimental controls and computational tools for the evaluation of library quality.

Keyphrases

randomized controlled trial
endothelial cells
molecularly imprinted
quality improvement
high resolution
liquid chromatography