Silencing integrated SIV proviral DNA with TAR-specific CRISPR tools.
Lisa M SmithVida L HodaraLaura M ParodiJessica E CalleryLuis D GiavedoniPublished in: Journal of medical primatology (2020)
Induction of epigenetic modifications may be more effective in inactivating provirus than transcriptional interference and thus may be a better strategy to achieve a functional cure in vivo.