Therapeutic drug monitoring of cefepime in a non-critically ill population: retrospective assessment and potential role for model-based dosing.

Veronique SuttelsPascal AndréYann ThomaFrançois VeuveLaurent Arthur DecosterdBenoît GueryThierry Buclin

Published in: JAC-antimicrobial resistance (2022)

Our observations support routine TDM of cefepime to prevent overdosing and subsequent toxicity in the non-critically ill. Software-based individualization seems promising to optimize the benefits of TDM, but has little potential to replace it.

Keyphrases

clinical practice
oxidative stress
cross sectional
human health
data analysis
risk assessment