Network meta-analysis of adjuvant chemotherapy in biliary tract cancers: Setting the scene for new randomized evidence.
Francesca SalaniGuglielmo VetereDaniele RossiniVirginia GenovesiMartina CarulloLinda BartaliniValentina MassaLaura BernardiniMiriam CacceseSilvia CesarioJessica GrazianiGiada GrelliFrancesco MangognaCaterina VivaldiGianluca MasiLorenzo FornaroPublished in: Liver international : official journal of the International Association for the Study of the Liver (2024)
Our work confirmed that adjuvant chemotherapy grants OS and EFS benefit for resected BTC patients. Fluoropyrimidines appeared the most effective option, confirming capecitabine as the preferred choice for the Western population.
Keyphrases
- systematic review
- end stage renal disease
- prognostic factors
- ejection fraction
- chronic kidney disease
- phase iii
- open label
- double blind
- lymph node
- randomized controlled trial
- south africa
- squamous cell carcinoma
- clinical trial
- meta analyses
- placebo controlled
- phase ii
- patient reported outcomes
- locally advanced
- patient reported
- phase ii study
- rectal cancer
- network analysis