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A Fictionalist Account of Open-Label Placebo.

Doug Hardman
Published in: The Journal of medicine and philosophy (2024)
The placebo effect is now generally defined widely as an individual's response to the psychosocial context of a clinical treatment, as distinct from the treatment's characteristic physiological effects. Some researchers, however, argue that such a wide definition leads to confusion and misleading implications. In response, they propose a narrow definition restricted to the therapeutic effects of deliberate placebo treatments. Within the framework of modern medicine, such a scope currently leaves one viable placebo treatment paradigm: the non-deceptive and non-concealed administration of "placebo pills" or open-label placebo (OLP) treatment. In this paper, I consider how the placebo effect occurs in OLP. I argue that a traditional, belief-based account of OLP is paradoxical. Instead, I propose an account based on the non-doxastic attitude of pretence, understood within a fictionalist framework.
Keyphrases
  • open label
  • phase iii
  • double blind
  • clinical trial
  • randomized controlled trial
  • radiation therapy
  • mental health
  • placebo controlled
  • replacement therapy
  • phase ii study
  • smoking cessation