Inhibition of allergen-induced dermal eosinophilia by an oxoeicosanoid receptor antagonist in non-human primates.
Lisa A MillerChantal CossetteShishir ChoureyQiuji YeChintam Nagendra ReddyJoshua RokachWilliam S PowellPublished in: British journal of pharmacology (2020)
5-Oxo-ETE may play an important role in allergen-induced eosinophilia. Blocking its effects with S-Y048 may provide a novel therapeutic approach for eosinophilic diseases.