Plasma mtDNA copy numbers are associated with GSTK1 expression and inflammation in type 2 diabetes.

X DengG YangX ZhengY YangH QinZ-X LiuH DengSong-Mei Liu

Published in: Diabetic medicine : a journal of the British Diabetic Association (2019)

mtDNA copy numbers in plasma might have an important role in the progression of diabetic chronic inflammation via inhibition of GSTK1 and could be a potential biomarker for type 2 diabetes.

Keyphrases

type diabetes
oxidative stress
mitochondrial dna
copy number
glycemic control
poor prognosis
cardiovascular disease
insulin resistance
binding protein
adipose tissue
dna methylation
genome wide
wound healing
skeletal muscle
weight loss