Microvascular dysfunction in patients with heart failure with preserved ejection fraction: A meta-analysis.

Mai AzumaShingo KatoKazuki FukuiNobuyuki HoritaDaisuke Utsunomiya

Published in: Microcirculation (New York, N.Y. : 1994) (2023)

This meta-analysis revealed that approximately 50% of patients diagnosed with HFpEF exhibited MVD. Moreover, the presence of MVD demonstrated significant prognostic implications in multiple studies conducted on patients with HFpEF. These findings strongly suggest that MVD plays a crucial role in the underlying pathophysiology of patients with HFpEF.

Keyphrases

systematic review
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
case control
oxidative stress
prognostic factors
randomized controlled trial
meta analyses
single cell