Multilevel regulation of RUVBL2 expression predicts poor prognosis in hepatocellular carcinoma.

Tao YanFang LiuJiajia GaoHaizhen LuJianqiang CaiXiaohang ZhaoYulin Sun

Published in: Cancer cell international (2019)

The deregulation of RUVBL2 in HCC is influenced at the genomic, epigenetic and transcriptional levels. Our findings highlight the potential roles of RUVBL2 as a promising prognostic marker as well as a therapeutic target for HCC.

Keyphrases

poor prognosis
long non coding rna
gene expression
dna methylation
transcription factor
copy number
human health