Lipid membranes accelerate amyloid formation in the mouse model of AA amyloidosis.

Aida Vahdat Shariat PanahiPer HultmanKarin ÖllingerGunilla T WestermarkKatarzyna Lundmark

Published in: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis (2019)

We conclude that increased intracellular lipid content facilitates AA amyloid fibril formation and show that the mouse model of AA amyloidosis is a suitable system for further mechanistic studies.

Keyphrases

mouse model
multiple myeloma
fatty acid
case control