Login / Signup

The Role of MicroRNAs in Parasitology.

Ozlem Ulusan BagciAyşe Caner
Published in: Turkiye parazitolojii dergisi (2020)
MicroRNAs (miRNAs), as epigenetic regulators, are small non-coding RNAs regulating gene expression in eukaryotes at the post-transcriptional level to control biological functions. MicroRNAs play a role in development, physiology, infection, immunity and the complex life cycles of parasites. Also, parasite infection can alter host miRNA expression that might result in either parasite clearance or infection. Over the past 20 years, thousands of miRNAs have been identified in the nematode Caenorhabditis elegans and other parasites. Thus, miRNA pathways are potential targets for the diagnostic and therapeutic control of parasitic diseases. Here, we review the current status and potential functions of miRNAs related to protozoans, helminths, and arthropods.
Keyphrases
  • gene expression
  • plasmodium falciparum
  • dna methylation
  • current status
  • transcription factor
  • poor prognosis
  • toxoplasma gondii
  • human health
  • risk assessment
  • heat shock protein
  • heat stress