TGFα expression in myeloid malignancies.

Simon KavanaghBob MirzaiKathy FullerWendy N Erber

Published in: Journal of clinical pathology (2016)

TGFα is expressed in neoplastic myeloblasts and could, therefore, be used as blast cell biomarker in diagnostic haematopathology. In addition, TGFα immunohistochemistry may be of use in identifying a therapeutic target.

Keyphrases

transforming growth factor
poor prognosis
epithelial mesenchymal transition
single cell
cell therapy
bone marrow
binding protein
immune response
signaling pathway
mesenchymal stem cells