ImmunoPET imaging of LAG-3 expression in tumor microenvironment with 68 Ga-labelled cyclic peptides tracers: from bench to bedside.

Ming ZhouBei ChenChenxi LuJinhui YangPeng LiuXiaobo WangShuo Hu

Published in: Journal for immunotherapy of cancer (2024)

Ga]Ga-CC09-1 is a promising PET tracer for quantifying the LAG-3 expression in tumor microenvironment, indicating its potential as a companion diagnostic for patients stratification and therapeutic response monitoring in anti-LAG-3 therapy.

Keyphrases

pet ct
poor prognosis
positron emission tomography
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
high resolution
computed tomography
prognostic factors
binding protein
stem cells
long non coding rna
bone marrow
mass spectrometry
cell therapy
smoking cessation
fluorescence imaging