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Identifying genetically-supported drug repurposing targets for non-small cell lung cancer through mendelian randomization of the druggable genome.

Yi FengCaichen LiBo ChengYing ChenPeiling ChenZixun WangXiangyuan ZhengJuan HeFeng ZhuWei WangWenhua Liang
Published in: Translational lung cancer research (2024)
Drugs targeting genetically supported genomes are considerably more likely to yield promising efficacy and succeed in clinical trials. We provide compelling genetic evidence to prioritize drug development for NSCLC.
Keyphrases
  • clinical trial
  • genome wide
  • small cell lung cancer
  • advanced non small cell lung cancer
  • cancer therapy
  • copy number
  • phase ii
  • randomized controlled trial
  • emergency department
  • drug delivery
  • tyrosine kinase