Identifying genetically-supported drug repurposing targets for non-small cell lung cancer through mendelian randomization of the druggable genome.
Yi FengCaichen LiBo ChengYing ChenPeiling ChenZixun WangXiangyuan ZhengJuan HeFeng ZhuWei WangWenhua LiangPublished in: Translational lung cancer research (2024)
Drugs targeting genetically supported genomes are considerably more likely to yield promising efficacy and succeed in clinical trials. We provide compelling genetic evidence to prioritize drug development for NSCLC.