Tracking cryptococcal meningitis to monitor HIV program success during the Treat-All era: an analysis of national data in Botswana.
James MilburnOokeditse NtwayagaeRachita SureshKebatshabile NgoniCassie NorthcottJames PennyMatthew KinsellaImogen MechieSamuel EnsorGoitseone ThamaeTshepo LeemeDavid S LawrenceTony ChebaniDaniel J GrintMark W TenfordeAva AvalosDinah RamaabyaJustus OgandoMargaret MokomaneMadisa MineJoseph N JarvisPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2024)
Cryptococcal meningitis incidence has decreased in Botswana following expansion of ART coverage but persists at a stubbornly high incidence. Most cases are now diagnosed through the cheap and easy-to-use cryptococcal antigen test highlighting the potential of using cryptococcal meningitis as key metric of programme success in the Treat All era.
Keyphrases
- cerebrospinal fluid
- antiretroviral therapy
- hiv infected
- quality improvement
- hiv positive
- human immunodeficiency virus
- hepatitis c virus
- hiv testing
- hiv aids
- study protocol
- clinical trial
- randomized controlled trial
- men who have sex with men
- risk assessment
- human health
- machine learning
- climate change
- south africa
- health insurance
- deep learning
- double blind