Short chain fatty acids and colon motility in a mouse model of irritable bowel syndrome.

Ilnar F ShaidullovDina M SorokinaFarit G SitdikovAnton HermannSayar R Abdulkhakov Guzel F Sitdikova

Published in: BMC gastroenterology (2021)

Our data indicate that the increased transit rate in the mouse IBS model group is associated with a disbalance of activating and inhibiting action of SCFAs due to chronically elevated SCFA levels, which may impact the pathogenesis of IBS with predominant diarrhea syndrome.

Keyphrases

irritable bowel syndrome
mouse model
signaling pathway
fatty acid
electronic health record
biofilm formation
big data
case report
data analysis
staphylococcus aureus
machine learning