Biomarkers involved in the proliferation of the odontogenic keratocyst, glandular odontogenic cyst and botryoid odontogenic cyst.
Joaquim Felipe JúniorGlória Maria De FrançaCaio César da Silva BarrosFernanda Aragão FélixWeslay Rodrigues da SilvaHévio Freitas de LucenaCláudia Nunes de OliveiraHébel Cavalcanti GalvãoPublished in: Oral and maxillofacial surgery (2022)
The high expression of EGFR in the cyst membrane suggests that EGF stimulates epithelial proliferation in BOCs, and the high expression of SOX2 in OKCs may be related to the presence of stem cells in the lesion. Cyclin D1 is related to cell cycle disruption in G1-S contributing to stimulates epithelial proliferation of OKCs and GOCs and BOCs.