Associations of depressive symptoms with white matter abnormalities and regional cerebral blood flow in patients with amnestic mild cognitive impairment.

Kentaro HiraoFumio YamashitaHikaru KatoKyoko KaneshiroAkito TsugawaRieko HaimeRaita FukasawaTomohiko SatoHidekazu KanetakaTakahiko UmaharaHirofumi SakuraiHaruo HanyuSoichiro Shimizu

Published in: Geriatrics & gerontology international (2022)

Depressive symptoms are significantly associated with PVH volume in MCI patients. The rCBF of the DLPFC was significantly associated with depressive symptoms, suggesting that this area might be closely involved in the pathogenesis of the depressive symptoms observed in MCI patients. Geriatr Gerontol Int 2022; 22: 846-850.

Keyphrases

depressive symptoms
mild cognitive impairment
end stage renal disease
cognitive decline
social support
ejection fraction
chronic kidney disease
newly diagnosed
white matter
peritoneal dialysis
prognostic factors
cerebral blood flow
sleep quality
patient reported outcomes
physical activity