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Mesenchymal Stromal Cell-Derived Extracellular Vesicles Pass through the Filtration Barrier and Protect Podocytes in a 3D Glomerular Model under Continuous Perfusion.

Linda BellucciGiovanni MontiniFederica CollinoBenedetta Bussolati
Published in: Tissue engineering and regenerative medicine (2021)
Using an innovative millifluidic model, able to mimic the human glomerular barrier, we were able to trace the EV passage and therapeutic effect in dynamic conditions.
Keyphrases
  • high glucose
  • endothelial cells
  • diabetic nephropathy
  • bone marrow
  • stem cells
  • heavy metals
  • contrast enhanced
  • pluripotent stem cells