Insulin resistance is associated with poorer verbal fluency performance in women.
Laura L EkbladJuha O RinnePauli J PuukkaHanna K LaineSatu E AhtiluotoRaimo O SulkavaMatti H ViitanenAntti M JulaPublished in: Diabetologia (2015)
To our knowledge, this is the first comprehensive, population-based study, including both young and middle-aged adults, to report that female sex impacts the association of HOMA-IR with verbal fluency. Our study was cross-sectional, so causal effects of HOMA-IR on cognition could not be evaluated. However, our results suggest that HOMA-IR could be an early marker for an increased risk of cognitive decline in women.
Keyphrases
- cognitive decline
- polycystic ovary syndrome
- middle aged
- mild cognitive impairment
- insulin resistance
- working memory
- cross sectional
- pregnancy outcomes
- healthcare
- adipose tissue
- metabolic syndrome
- cervical cancer screening
- breast cancer risk
- high fat diet
- white matter
- pregnant women
- multiple sclerosis
- high fat diet induced