High-circulating gut microbiota-dependent metabolite trimethylamine N-oxide is associated with poor prognosis in pulmonary arterial hypertension.
Yicheng YangQi-Xian ZengJianing GaoBeilan YangJingjing ZhouKe LiLi LiAnxin WangXin LiZhihong LiuQin LuoZhihui ZhaoBingyang LiuJing XueXue JiangMatthew C KonermanLemin ZhengChangming XiongPublished in: European heart journal open (2022)
Increased TMAO levels were associated with poor prognosis in patients with PAH, and DMB played a protective effect in MCT-induced PAH rat.