Changes in brain response to urgency before and after treatment of urgency urinary incontinence with onabotulinumtoxin A.

Becky D ClarksonHelmet T KarimChristopher J ChermanskyLayla BanihashemiShachi TyagiDerek J GriffithsNeil M Resnick

Published in: Neurourology and urodynamics (2022)

The changes seen in the brain control mechanism after therapy likely reflect reduced bladder sensation caused by BoNTA's peripheral action. We ascribe the SMG and IFG changes to a coping mechanism for urgency which is reduced in those who respond well to treatment.

Keyphrases

urinary incontinence
resting state
white matter
functional connectivity
cerebral ischemia
spinal cord injury
social support
stem cells
bone marrow
combination therapy
brain injury
chemotherapy induced
replacement therapy
smoking cessation
cell therapy