Transitioning Hospitalized Patients with Opioid Use Disorder from Methadone to Buprenorphine without a Period of Opioid Abstinence Using a Microdosing Protocol.

A protocol using microdosing of buprenorphine can successfully transition patients receiving full μ-opioid agonist therapy, including methadone, to buprenorphine without the need for a period of opioid abstinence.